During the study, 130 medical records of patients were analyzed using statistical methods such as the Mann-Whitney criterion, χ², and the calculation of relative odds using the StatTech v.4.8.7 program.
The data obtained showed that polypharmacy is observed in 48.5% of patients and has a significant correlation with advanced stages of cancer (54% compared to 20.9%), the appointment of palliative care (76.2% versus 46.3%), and frequent therapy interruptions (65.1% compared to 20.9%; odds ratio calculation = 7). Such patients are diagnosed with more severe comorbidities; however, echocardiographic studies are performed less frequently (65.1% versus 80.6%).
The researchers emphasize that polypharmacy serves as an indicator of the complex clinical status of patients. This necessitates the creation of optimized treatment management algorithms, increased cardiomonitoring, and mandatory echocardiograms, which should improve treatment safety.
This study highlights the need for a comprehensive approach in the therapy of cancer patients with cardiovascular diseases and the integration of cardiological monitoring into standard clinical protocols.
