Scientists analyzed autopsy data from 35 patients who died from the flu and found that 85% of them had at least one chronic heart condition, with many having multiple pathologies. These results confirmed that cardiovascular diseases can be key factors in flu-related mortality.
During the study, a new subpopulation of white blood cells, known as pro-dendritic cells 3, was identified. These cells migrate from the lungs to the heart, where they produce a significant amount of type 1 interferon. However, instead of fighting the virus, this process leads to the destruction of cardiomyocytes.
Experiments showed that the use of a drug targeting type 1 interferon can effectively reduce heart damage and improve its functionality. The scientists' future plans include developing a therapy that simultaneously reduces heart damage after viral infections and supports the antiviral immune response.
It is worth noting that not only the flu but also other viruses, such as COVID-19, significantly increase the risks of stroke and heart attack, according to data from another study, where the risks increased up to seven times.
